The Nobel Prize 2025 in Medicine has been awarded to Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi for work on peripheral immune tolerance.
64-year-old Brunkow is a senior program manager at the Institute for Systems Biology in Seattle. Ramsdell (64) is a scientific adviser for Sonoma Biotherapeutics in San Francisco. 74-year-old Sakaguchi is a distinguished professor at the Immunology Frontier Research Center at Osaka University in Japan. Peripheral immune tolerance is one way the body helps keep the immune system from getting out of whack and attacking its own tissues instead of foreign invaders.
